ABSTRACT
INTRODUCTION: Dysgenesis of the corpus callosum is a brain abnormality involving the large nerve fibers connecting the two hemispheres of the brain. The corpus callosum connects the left and right cerebral hemispheres and facilitates interhemispheric communication. When it is malformed, these functions might be affected. CLINICAL PRESENTATION: This case report documents a patient with a malformed corpus callosum. She came in for first-onset generalized tonic clonic seizures. As part of a routine workup for patients with first-onset seizures,a computed tomography (CT) scan of the brain was done. It revealed dysgenesis of the corpus callosum. She was started on valproic acid and was discharged improved. CONCLUSION: Callosal disorders usually present with some degree of neurologic impairment. The index case however has no detectable neurologic deficits and is apparently normal. The rarity of a dysgenetic corpus callosum mandates more epidemiological studies to further elucidate this disease.